Zepar Tablets are a formulation containing albendazole, an antiparasitic medication used to treat various infections caused by parasitic worms. The specific dosage of 400 mg indicates that these tablets are intended for the treatment of more severe or resistant infections.
Key Features
- Active Ingredient: Each tablet contains 400 mg of albendazole.
- Packaging: Typically available in a pack of 2 tablets.
Indications
Zepar is indicated for the treatment of:
- Intestinal Helminth Infections: Effective against:
- Roundworms (Ascaris)
- Hookworms (Ancylostoma, Necator)
- Whipworms (Trichuris)
- Pinworms (Enterobius)
- Tapeworms (Taenia)
- Tissue Infections: Such as:
- Neurocysticercosis (caused by the larval form of the pork tapeworm)
- Cystic hydatid disease (caused by the dog tapeworm)
Mechanism of Action
Albendazole works by inhibiting the polymerization of tubulin, which disrupts the metabolism of the parasites. This leads to energy depletion and immobilization, ultimately resulting in the death of the worms.
Dosage and Administration
- Recommended Dosage:
- For adults and children over 2 years: A common regimen is 400 mg orally once, or as prescribed by a healthcare provider.
- For specific infections like neurocysticercosis or hydatid disease, higher or more prolonged dosing may be required based on weight and severity.
- Administration Tips: Swallow the tablet whole with water. It is most effective when taken with food to enhance absorption.
Side Effects
Common side effects may include:
- Nausea
- Vomiting
- Abdominal pain
- Headache
- Dizziness
Serious side effects requiring immediate medical attention include:
- Signs of severe allergic reactions (e.g., rash, swelling).
- Symptoms of liver dysfunction (e.g., jaundice).
Precautions
- Contraindications: Not recommended for individuals with known hypersensitivity to albendazole or any other components. Caution is advised for those with liver disease or bone marrow suppression.
- Pregnancy and Breastfeeding: Should not be used during pregnancy unless clearly needed. Consult a healthcare provider before use if pregnant or breastfeeding.
- Drug Interactions: Inform your healthcare provider about any other medications being taken to avoid potential interactions.
