Terbinafine Cream is a topical antifungal medication used to treat various fungal skin infections. It contains terbinafine hydrochloride as the active ingredient, which is effective against dermatophytes and some yeasts.
Key Features
- Active Ingredient: Each gram of cream typically contains 10 mg of terbinafine hydrochloride.
- Formulation: The cream is designed for topical application and is available in various strengths, commonly at 1% concentration.
Indications
Terbinafine Cream is indicated for the treatment of:
- Tinea Pedis (Athlete's Foot): A fungal infection affecting the feet.
- Tinea Cruris (Jock Itch): A fungal infection in the groin area.
- Tinea Corporis (Ringworm): A fungal infection that can occur on various parts of the body.
- Pityriasis Versicolor: A skin condition caused by Malassezia yeast, characterized by discolored patches on the skin.
Mechanism of Action
Terbinafine works by inhibiting the enzyme squalene epoxidase, which is crucial for fungal cell membrane synthesis. This action prevents the growth and reproduction of fungi, effectively treating the infection.
Dosage and Administration
- Application Frequency:
- For Tinea Pedis: Apply to the affected area twice daily.
- For Tinea Cruris and Tinea Corporis: Apply once daily.
- For Pityriasis Versicolor: Apply twice daily.
- Duration of Treatment:
- Tinea infections usually require treatment for 1 to 4 weeks depending on the specific condition and severity.
Side Effects
Common side effects may include:
- Burning or stinging at the application site
- Redness or irritation
- Dryness or peeling of the skin
Serious side effects that require immediate medical attention include:
- Severe allergic reactions (e.g., hives, swelling of face or throat)
- Signs of infection worsening (e.g., increased redness, swelling, or oozing)
Precautions
- Avoid Contact with Eyes: Terbinafine may irritate the eyes; if contact occurs, rinse thoroughly with water.
- Not for Oral Use: This cream is intended for external use only and should not be ingested or applied to mucous membranes.
- Pregnancy and Breastfeeding: Consult a healthcare provider before using this medication if pregnant or breastfeeding.