Plasil is a brand name for Metoclopramide, an antiemetic medication used primarily to prevent nausea and vomiting. It is particularly effective in managing symptoms associated with various medical conditions, including those related to surgery and chemotherapy.
Key Features
- Active Ingredient: Each 2ml injection of Plasil contains Metoclopramide Hydrochloride, which acts as a dopamine D2 receptor antagonist.
- Formulation: The injection is typically administered intramuscularly (IM) or intravenously (IV).
Indications
Plasil is indicated for:
- Nausea and Vomiting: Effective in preventing nausea and vomiting caused by chemotherapy, surgery, or other medical conditions.
- Gastroparesis: Used to treat symptoms of delayed gastric emptying in diabetic patients, such as nausea, vomiting, and feeling of fullness.
- Facilitating Intubation: Helps in procedures requiring the placement of tubes into the stomach or intestines by promoting gastric emptying.
Dosage Instructions
- Adults: The usual dose for nausea and vomiting is 10 mg to 20 mg administered IM or IV, depending on the severity of symptoms.
- Pediatric Patients (over 14 years): Typically, a dose of 10 mg IV may be administered.
- For specific conditions such as gastroparesis, doses may vary based on clinical response and physician recommendations.
Administration
- Plasil should be administered by a healthcare professional.
- The injection can be given slowly over a period of 1 to 2 minutes when administered IV.
Side Effects
Common side effects may include:
- Drowsiness or sedation
- Dizziness
- Fatigue
- Diarrhea
Serious side effects can include:
- Extrapyramidal symptoms (e.g., muscle spasms or uncontrolled movements)
- Allergic reactions (e.g., rash, swelling)
- Cardiovascular issues in rare cases
Precautions
- Contraindications: Not recommended for individuals with known hypersensitivity to metoclopramide or those with conditions such as gastrointestinal obstruction or perforation.
- Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding.
- Elderly Patients: Use with caution due to the increased risk of side effects.
