Panadol Advance is a widely used over-the-counter medication designed for the relief of pain and reduction of fever. Each pack typically contains 100 tablets (10 strips of 10 tablets each), making it convenient for both short-term and long-term use.
Key Ingredients
- Paracetamol (Acetaminophen): Each tablet contains 500 mg of paracetamol, which is effective for alleviating mild to moderate pain and reducing fever. Common uses include:
- Headaches
- Toothaches
- Muscle aches
- Menstrual cramps
- Symptoms associated with colds and flu
Mechanism of Action
Paracetamol works by inhibiting the production of prostaglandins in the brain, which are chemicals that promote pain and inflammation. It also acts on the hypothalamic heat-regulating center to lower body temperature.
Dosage and Administration
- Recommended Dosage:
- For adults and children aged 12 years and over: Take 1 to 2 tablets every 4 to 6 hours as needed, not exceeding 8 tablets in a 24-hour period.
- For children aged 10 to 15 years: Administer 1 tablet every 4 to 6 hours as needed, with a maximum of 4 tablets in a 24-hour period. Do not give for more than 3 days without consulting a doctor.
- Administration Instructions: Swallow the tablets whole with water. It can be taken with or without food; however, taking it after meals may help reduce gastrointestinal discomfort.
Side Effects
Common side effects may include:
- Nausea
- Vomiting
- Stomach pain
- Allergic reactions (rare), such as skin rash or swelling
Serious side effects are rare but can include:
- Liver damage, particularly with overdose or prolonged use.
- Severe allergic reactions requiring immediate medical attention.
Precautions
- Contraindications: Avoid use if allergic to paracetamol or any other components of the medication. Caution is advised for individuals with liver disease or chronic alcoholism.
- Pregnancy and Breastfeeding: Generally considered safe, but consult a healthcare provider before use.
- Drug Interactions: Inform your healthcare provider about all medications you are taking, especially those that may contain paracetamol.
