Olfen SR is a sustained-release formulation of Diclofenac Sodium, a non-steroidal anti-inflammatory drug (NSAID) used for the management of pain and inflammation. The 100mg dosage indicates a higher strength, suitable for patients requiring effective long-term relief from various inflammatory conditions.
Key Uses
Olfen SR is indicated for:
- Osteoarthritis: Provides relief from pain and stiffness associated with this degenerative joint disease.
- Rheumatoid Arthritis: Helps manage symptoms such as inflammation, swelling, and joint pain.
- Ankylosing Spondylitis: Effective in treating this chronic inflammatory condition affecting the spine.
- Postoperative Pain: Used to alleviate pain following surgical procedures.
Mechanism of Action
Diclofenac works by inhibiting the enzymes (COX-1 and COX-2) involved in the production of prostaglandins, which are responsible for pain and inflammation. By reducing these substances, Olfen SR effectively decreases pain and swelling.
Dosage and Administration
- Recommended Dosage:
- The typical adult dosage is 100 mg once daily. Depending on the severity of symptoms, your healthcare provider may adjust the dosage.
- Administration Instructions:
- Take the capsule with a full glass of water, preferably after meals to minimize gastrointestinal irritation. Do not crush or chew the capsule; swallow it whole.
Side Effects
Common side effects may include:
- Gastrointestinal issues such as nausea, vomiting, diarrhea, or constipation.
- Headache or dizziness.
- Increased blood pressure.
- Skin reactions like rash or itching.
Serious side effects can include:
- Signs of gastrointestinal bleeding (e.g., black or tarry stools).
- Severe allergic reactions (e.g., swelling, difficulty breathing).
- Symptoms of heart problems (e.g., chest pain, shortness of breath).
- Liver or kidney issues (e.g., jaundice, reduced urine output).
Precautions
- Contraindications: Avoid use in individuals with known allergies to diclofenac or other NSAIDs. Not recommended for patients with active peptic ulcers or severe renal impairment.
- Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding.