Montelukast 10mg Tablets (Unicast) are a prescription medication used primarily for the management of asthma and the relief of symptoms associated with allergic rhinitis. Montelukast is classified as a leukotriene receptor antagonist, which helps to reduce inflammation in the airways and improve breathing.
Key Uses
Montelukast is indicated for:
- Asthma Management: Helps prevent wheezing and shortness of breath caused by asthma and decreases the frequency of asthma attacks.
- Allergic Rhinitis: Provides relief from symptoms such as sneezing, runny or stuffy nose, and itchy eyes caused by seasonal or perennial allergies.
- Exercise-Induced Bronchoconstriction: Used to prevent breathing difficulties during exercise in individuals aged 6 years and older.
Mechanism of Action
Montelukast works by blocking leukotrienes, which are substances in the body that cause airway inflammation, bronchoconstriction, and mucus production. By inhibiting these actions, montelukast helps to keep airways open and reduces allergy symptoms.
Dosage and Administration
- Recommended Dosage: The typical dosage for adults and adolescents aged 15 years and older is 10 mg once daily, taken in the evening. For children aged 6 to 14 years, the dosage is usually 5 mg once daily, while children aged 2 to 5 years typically receive 4 mg once daily.
- Administration Instructions: Montelukast can be taken with or without food. It is important to take it at the same time each day for optimal effectiveness.
Side Effects
Common side effects may include:
- Headache
- Stomach pain
- Diarrhea
- Fatigue
- Upper respiratory infections (e.g., sinusitis)
Serious side effects can include:
- Neuropsychiatric Events: Some users have reported mood changes, agitation, aggression, anxiety, depression, sleep disturbances, and suicidal thoughts or actions.
- Churg-Strauss Syndrome: A rare condition characterized by blood vessel inflammation that can occur in patients with asthma or those taking oral corticosteroids.
- Allergic Reactions: Symptoms may include rash, swelling of the face or throat, and difficulty breathing.
Precautions
- Contraindications: Avoid use in individuals with known hypersensitivity to montelukast.
- Mental Health History: Inform your healthcare provider if you have a history of mental health issues, as montelukast may exacerbate these conditions.
- Pregnancy and Breastfeeding: Consult a healthcare provider before use if pregnant or breastfeeding.
