Nucoxia is a medication that contains Etoricoxib as its active ingredient. It belongs to the class of drugs known as non-steroidal anti-inflammatory drugs (NSAIDs), specifically a selective COX-2 inhibitor. Nucoxia is primarily used for managing pain and inflammation associated with various conditions.
Key Uses
Nucoxia 120mg is indicated for:
- Osteoarthritis: Provides relief from pain and inflammation related to degenerative joint disease.
- Rheumatoid Arthritis: Helps manage symptoms of joint inflammation and pain in this autoimmune condition.
- Ankylosing Spondylitis: Treats inflammation and stiffness primarily affecting the spine.
- Acute Gouty Arthritis: Reduces pain and inflammation during acute gout attacks.
- Postoperative Pain: Assists in managing pain following surgical procedures.
Mechanism of Action
Etoricoxib selectively inhibits the COX-2 enzyme, which plays a key role in the inflammatory process. By blocking this enzyme, Nucoxia effectively reduces pain and swelling while minimizing gastrointestinal side effects compared to traditional NSAIDs.
Dosage and Administration
- Recommended Dosage: The typical dosage for adults is 120 mg once daily, especially for acute conditions like gout. For chronic conditions like osteoarthritis or rheumatoid arthritis, lower doses (30 mg to 90 mg) may be used based on the severity of symptoms.
- Administration Instructions: It can be taken with or without food. It is advisable to take it at a fixed time each day for optimal results.
Side Effects
Common side effects associated with Nucoxia may include:
- Stomach pain
- Nausea and vomiting
- Dizziness
- Headache
- Swelling of legs or feet (edema)
- Rapid heartbeat
- Mouth ulcers
Serious side effects can include:
- Signs of gastrointestinal bleeding (e.g., black or bloody stools)
- Severe allergic reactions (e.g., rash, swelling)
- Increased blood pressure or heart-related issues
Contraindications
Nucoxia should not be used in individuals who:
- Are allergic to etoricoxib or any other components of the medication.
- Have severe liver or kidney disease.
- Have a history of peptic ulcers or gastrointestinal bleeding.
- Are under 16 years of age.
- Are pregnant or breastfeeding without consulting a healthcare provider.
- Have uncontrolled high blood pressure or significant heart disease.
Precautions
- Regular monitoring of kidney function is recommended during prolonged use.
- Patients with existing cardiovascular conditions should use this medication with caution due to potential risks.
