Nifedipine is a calcium channel blocker primarily used to treat hypertension (high blood pressure) and angina (chest pain). The 20mg formulation from Cadila is designed for effective management of these conditions.
Key Uses
Nifedipine is indicated for:
- Hypertension: Helps lower blood pressure, reducing the risk of heart disease and stroke.
- Angina Pectoris: Relieves chest pain by improving blood flow to the heart muscle.
- Vasospastic Angina: Effective in treating chest pain caused by spasms of the coronary arteries.
Mechanism of Action
Nifedipine works by blocking calcium channels in vascular smooth muscle, leading to relaxation and dilation of blood vessels. This action reduces peripheral vascular resistance, thereby lowering blood pressure and decreasing the workload on the heart.
Dosage and Administration
- Recommended Dosage: The usual starting dose for adults is 20 mg, taken three times a day. The dosage may be adjusted based on individual response and physician guidance.
- Administration Instructions: Nifedipine should be taken orally, swallowed whole with water. It can be taken with or without food, but consistency regarding meals is recommended.
Side Effects
Common side effects may include:
- Dizziness or lightheadedness
- Flushing (redness of the skin)
- Swelling of extremities (ankles or feet)
- Headache
- Nausea
- Heartburn
Serious side effects can include:
- Severe allergic reactions (e.g., rash, swelling)
- Chest pain or worsening angina
- Symptoms of liver dysfunction (e.g., jaundice)
- Hypotension (low blood pressure), which may cause fainting or dizziness
Precautions
- Contraindications: Avoid use in individuals with known hypersensitivity to Nifedipine or those with severe hypotension.
- Pregnancy and Breastfeeding: Consult a healthcare provider before use if pregnant or breastfeeding.
- Drug Interactions: Inform your healthcare provider about all medications being taken, as Nifedipine may interact with other antihypertensive agents or medications affecting heart function.
