Hydralazine is a medication primarily used for the treatment of high blood pressure (hypertension) and certain heart conditions. It is classified as a vasodilator, which means it works by relaxing the muscles in blood vessels, allowing them to widen and improve blood flow.
Key Features
- Active Ingredient: Hydralazine hydrochloride
- Strength: 25 mg per tablet
- Pack Size: Typically available in packs of 100 tablets.
Indications
Hydralazine is indicated for:
- Hypertension: Used to manage moderate to severe high blood pressure, often in combination with other antihypertensive medications.
- Heart Failure: Sometimes prescribed alongside nitrates for patients with chronic heart failure.
Mechanism of Action
Hydralazine works by:
- Dilating Blood Vessels: It directly relaxes arterial smooth muscle, leading to decreased systemic vascular resistance and lower blood pressure.
- Increasing Blood Flow: Enhances blood supply to the heart, which can be beneficial in certain cardiac conditions.
Dosage and Administration
- Recommended Dosage:
- Adults: The typical starting dose is often 10 mg to 25 mg, taken 2 to 4 times daily. The dosage may be adjusted based on individual response and tolerance.
- Administration Instructions:
- Take the tablets with a full glass of water. Consistency in taking the medication (with or without food) is important for optimal absorption.
Side Effects
Common side effects may include:
- Headache
- Nausea or vomiting
- Diarrhea
- Fast or pounding heartbeat
- Chest pain
Serious side effects can include:
- Lupus-like syndrome (joint pain, fever, rash)
- Chest pain indicating potential heart issues
- Severe allergic reactions (e.g., hives, difficulty breathing)
Precautions
- Contraindications: Not suitable for individuals with known hypersensitivity to hydralazine or those with certain heart conditions (e.g., coronary artery disease).
- Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding.
- Drug Interactions: Inform your healthcare provider about any other medications you are taking to avoid potential interactions.
