Duphaston 10mg Tablets contain Dydrogesterone, a synthetic progestogen used primarily in the treatment of various conditions related to progesterone deficiency in women. Each pack typically contains 20 tablets.
Key Features
- Active Ingredient: Each tablet contains 10 mg of Dydrogesterone.
- Formulation: Oral tablets designed for easy administration.
Indications
Duphaston is indicated for:
- Menstrual Disorders: Treatment of irregular menstrual cycles and dysmenorrhea (painful periods).
- Premenstrual Syndrome (PMS): Helps alleviate symptoms associated with PMS.
- Endometriosis: Used to manage symptoms by preventing the growth of endometrial tissue outside the uterus.
- Infertility: Assists in cases of luteal phase insufficiency, supporting pregnancy.
- Threatened or Habitual Abortion: Used to stabilize pregnancies at risk due to low progesterone levels.
Mechanism of Action
Dydrogesterone mimics the effects of natural progesterone, helping to regulate the menstrual cycle, support pregnancy, and reduce the symptoms associated with hormonal imbalances. It works by:
- Preparing the endometrium for implantation of a fertilized egg.
- Preventing abnormal uterine bleeding.
- Reducing the growth of endometrial tissue in conditions like endometriosis.
Dosage and Administration
- Recommended Dosage:
- For menstrual disorders and PMS: Typically, 10 mg twice daily from day 11 to day 25 of the menstrual cycle.
- For endometriosis: 10 mg two to three times daily from day 5 to day 25 of the cycle, or as directed by a healthcare provider.
- For threatened abortion: Initial dose may be higher, starting with 4 tablets at once, followed by 1 tablet every 8 hours.
- Administration Instructions:
- Take the tablets orally with water, with or without food.
- Swallow whole; do not chew or crush.
Side Effects
Common side effects may include:
- Nausea and vomiting
- Breast tenderness or pain
- Headaches or migraines
- Mood swings or depression
- Abdominal pain
Serious side effects are rare but can include:
- Severe allergic reactions (e.g., rash, swelling).
- Unexplained vaginal bleeding that requires medical attention.
If any severe reactions occur, discontinue use immediately and seek medical help.
Precautions
- Contraindications: Duphaston should not be used if you have:
- Known hypersensitivity to Dydrogesterone or other ingredients.
- Unexplained vaginal bleeding.
- A history of hormone-dependent tumors (e.g., breast cancer).
- Caution Required: Use with caution in patients with liver disease, history of thromboembolic disorders, or those who smoke. Regular monitoring may be necessary during treatment.
- Pregnancy and Breastfeeding: Consult a healthcare provider before use if pregnant or breastfeeding.
