Doxazosin 4mg Tablets are a medication primarily used for the treatment of hypertension (high blood pressure) and symptoms associated with benign prostatic hyperplasia (BPH), which is an enlargement of the prostate gland. Doxazosin belongs to a class of medications known as alpha-blockers, which work by relaxing blood vessels and improving urine flow in men with BPH.
Key Features
- Active Ingredient: Each tablet contains 4 mg of Doxazosin (as doxazosin mesilate).
- Formulation: Oral tablets, typically available in packs of 28 tablets.
Indications
Doxazosin is indicated for:
- Hypertension: Helps lower blood pressure by relaxing blood vessels, making it easier for the heart to pump blood.
- Benign Prostatic Hyperplasia (BPH): Alleviates urinary symptoms associated with an enlarged prostate, such as difficulty urinating or frequent urination.
Mechanism of Action
Doxazosin works by blocking alpha-1 adrenergic receptors in the smooth muscle of blood vessels and the prostate. This action leads to:
- Relaxation of vascular smooth muscle, resulting in decreased peripheral resistance and lower blood pressure.
- Relaxation of smooth muscle in the prostate and bladder neck, improving urine flow.
Dosage and Administration
- Recommended Dosage: The typical starting dose for hypertension is 1 mg, which may be gradually increased to a maximum of 16 mg per day based on individual response. For BPH, the usual starting dose is also 1 mg, with potential increases.
- Administration Instructions: Take the tablet once daily, preferably at the same time each day. It can be taken with or without food. Swallow the tablet whole with a glass of water.
Side Effects
Common side effects may include:
- Dizziness or lightheadedness, especially when standing up (orthostatic hypotension)
- Fatigue or drowsiness
- Headache
- Swelling in the hands or feet (edema)
- Nausea
Serious side effects can include:
- Severe allergic reactions (e.g., hives, difficulty breathing)
- Rapid or irregular heartbeat
- Chest pain
- Prolonged erection (priapism)
If any severe reactions occur, discontinue use immediately and seek medical attention.
Precautions
- Contraindications: Not recommended for individuals with known hypersensitivity to Doxazosin or other components of the formulation, severe liver impairment, or those taking certain medications that may interact adversely.
- Caution Required: Use with caution in patients with existing cardiovascular conditions, liver or kidney impairment, and those undergoing cataract surgery (due to potential intraoperative floppy iris syndrome).
- Pregnancy and Breastfeeding: Consult a healthcare provider before use if pregnant or breastfeeding.
Doxazosin 4mg Tablets are a medication primarily used for the treatment of hypertension (high blood pressure) and symptoms associated with benign prostatic hyperplasia (BPH), which is an enlargement of the prostate gland. Doxazosin belongs to a class of medications known as alpha-blockers, which work by relaxing blood vessels and improving urine flow in men with BPH.
Key Features
- Active Ingredient: Each tablet contains 4 mg of Doxazosin (as doxazosin mesilate).
- Formulation: Oral tablets, typically available in packs of 28 tablets.
Indications
Doxazosin is indicated for:
- Hypertension: Helps lower blood pressure by relaxing blood vessels, making it easier for the heart to pump blood.
- Benign Prostatic Hyperplasia (BPH): Alleviates urinary symptoms associated with an enlarged prostate, such as difficulty urinating or frequent urination.
Mechanism of Action
Doxazosin works by blocking alpha-1 adrenergic receptors in the smooth muscle of blood vessels and the prostate. This action leads to:
- Relaxation of vascular smooth muscle, resulting in decreased peripheral resistance and lower blood pressure.
- Relaxation of smooth muscle in the prostate and bladder neck, improving urine flow.
Dosage and Administration
- Recommended Dosage: The typical starting dose for hypertension is 1 mg, which may be gradually increased to a maximum of 16 mg per day based on individual response. For BPH, the usual starting dose is also 1 mg, with potential increases.
- Administration Instructions: Take the tablet once daily, preferably at the same time each day. It can be taken with or without food. Swallow the tablet whole with a glass of water.
Side Effects
Common side effects may include:
- Dizziness or lightheadedness, especially when standing up (orthostatic hypotension)
- Fatigue or drowsiness
- Headache
- Swelling in the hands or feet (edema)
- Nausea
Serious side effects can include:
- Severe allergic reactions (e.g., hives, difficulty breathing)
- Rapid or irregular heartbeat
- Chest pain
- Prolonged erection (priapism)
If any severe reactions occur, discontinue use immediately and seek medical attention.
Precautions
- Contraindications: Not recommended for individuals with known hypersensitivity to Doxazosin or other components of the formulation, severe liver impairment, or those taking certain medications that may interact adversely.
- Caution Required: Use with caution in patients with existing cardiovascular conditions, liver or kidney impairment, and those undergoing cataract surgery (due to potential intraoperative floppy iris syndrome).
- Pregnancy and Breastfeeding: Consult a healthcare provider before use if pregnant or breastfeeding.
