CEBAY is an oral suspension containing cefixime, a third-generation cephalosporin antibiotic. This formulation is typically used to treat various bacterial infections due to its effectiveness against a broad spectrum of bacteria.
Key Uses
Cefixime is indicated for the treatment of:
- Urinary Tract Infections (UTIs): Effective against infections caused by susceptible strains of Escherichia coli and Proteus mirabilis.
- Otitis Media: Treats middle ear infections caused by Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus pneumoniae.
- Tonsillitis/Pharyngitis: Used for infections caused by Streptococcus pyogenes.
- Bronchitis and Pneumonia: Effective in treating acute exacerbations of chronic bronchitis and pneumonia.
- Gonorrhea: Treats uncomplicated gonococcal infections caused by Neisseria gonorrhoeae.
Mechanism of Action
Cefixime works by inhibiting bacterial cell wall synthesis, which is essential for bacterial growth and survival. By disrupting this process, cefixime effectively kills the bacteria, helping to clear the infection.
Dosage and Administration
- Typical Dosage: The dosage for adults is usually 400 mg once daily or 200 mg every 12 hours. For children, the dosage is often based on weight (8 mg/kg/day for children under 45 kg).
- Administration: The suspension should be shaken well before use. It can be taken with or without food, but taking it consistently at the same time each day helps maintain even levels in the bloodstream.
Side Effects
Common side effects may include:
- Nausea
- Diarrhea
- Abdominal pain
- Headache
- Dizziness
Serious side effects can include:
- Severe allergic reactions (rash, itching, swelling)
- Clostridium difficile-associated diarrhea
- Liver dysfunction (jaundice)
- Kidney problems
Warnings and Precautions
- Contraindications: Should not be used in individuals with known allergies to cefixime or other cephalosporins.
- Drug Interactions: May interact with other medications; inform your healthcare provider about all medications being taken.
- Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding.
Storage
Store CEBAY (Cefixime) at room temperature, away from moisture and direct sunlight. After reconstitution, the suspension should typically be refrigerated and used within a specified period (usually 14 days).
