Bromocriptine, marketed under the brand name Dopagon, is a medication primarily used to treat conditions related to hormonal imbalances, particularly those associated with excess prolactin. It is also utilized in the management of Parkinson's disease and certain types of acromegaly.
Key Features
- Formulation: Each tablet typically contains 2.5 mg of bromocriptine.
- Packaging: Available in a pack of 20 tablets.
Indications
Bromocriptine is indicated for:
- Hyperprolactinemia: Treatment of conditions caused by elevated prolactin levels, such as prolactinomas (pituitary tumors that secrete prolactin).
- Parkinson's Disease: Used as part of a treatment regimen to manage symptoms.
- Acromegaly: Helps reduce growth hormone levels in patients with acromegaly when surgery is not an option or as an adjunct to surgery.
Mechanism of Action
Bromocriptine is a dopamine agonist that works by stimulating dopamine receptors in the brain. This action leads to decreased secretion of prolactin from the pituitary gland and helps alleviate symptoms associated with excessive prolactin levels.
Dosage and Administration
- Recommended Dosage: The dosage may vary based on the condition being treated. Typically, treatment starts at a low dose, which can be gradually increased.
- For hyperprolactinemia, an initial dose may be around 1.25 mg daily, which can be increased based on tolerance and response.
- Administration: Take the tablet with food to minimize gastrointestinal side effects.
Side Effects
Common side effects may include:
- Nausea or vomiting
- Dizziness or lightheadedness
- Fatigue or drowsiness
- Headaches
- Constipation
Warnings and Precautions
- Contraindications: Not suitable for individuals with known hypersensitivity to bromocriptine or other components of the formulation, uncontrolled hypertension, or certain cardiovascular conditions.
- Caution in Special Populations: Use with caution in patients with a history of mental health issues, as bromocriptine can affect mood and behavior.
- Pregnancy and Breastfeeding: Consult a healthcare provider before use if pregnant or breastfeeding.
Storage
Store Bromocriptine tablets at room temperature (below 25°C), away from moisture and direct sunlight. Keep out of reach of children.
