Betanase is an anti-diabetic medication that contains glibenclamide (also known as glyburide) as its active ingredient. It is primarily used for the management of type 2 diabetes mellitus by helping to control blood sugar levels.
Key Features
- Active Ingredient: Glibenclamide (5 mg per tablet).
- Formulation: Available in a pack of 150 tablets.
Indications
Betanase is indicated for:
- Type 2 Diabetes Mellitus: It is used in conjunction with diet and exercise to improve glycemic control in adults with type 2 diabetes.
Mechanism of Action
Glibenclamide works by:
- Stimulating Insulin Release: It stimulates the pancreas to release more insulin, which helps lower blood sugar levels.
- Improving Insulin Sensitivity: It may also enhance the body's sensitivity to insulin.
Dosage and Administration
- Recommended Dosage: The typical starting dose is 5 mg daily, which can be adjusted based on blood glucose levels and individual response.
- Administration: Betanase should be taken just before or with meals to reduce the risk of hypoglycemia (low blood sugar).
Side Effects
Possible side effects may include:
- Common Side Effects:
- Headache
- Dizziness
- Nausea
- Vomiting
- Hypoglycemia (low blood sugar), which may cause symptoms such as sweating, shakiness, confusion, and irritability.
- Serious Side Effects:
- Allergic reactions (rash, itching, difficulty breathing).
- Liver or kidney problems.
Contraindications
Betanase should not be used in individuals who:
- Are allergic to glibenclamide or any other ingredients in the formulation.
- Have type 1 diabetes or are in a diabetic coma.
- Have severe liver or kidney impairment.
- Are pregnant or breastfeeding without medical advice.
Warnings and Precautions
- Regular Monitoring: Regular monitoring of blood glucose levels is essential while on this medication.
- Diet and Exercise: Patients should maintain a proper diet and exercise regimen to achieve optimal results.
- Alcohol Consumption: Alcohol can increase the risk of hypoglycemia; caution is advised.
Storage
Store Betanase tablets at room temperature (below 25°C), away from moisture and direct sunlight. Keep out of reach of children.
