Benzhexol (Trihexyphenidyl hydrochloride) is a medication primarily used for the symptomatic treatment of Parkinson's disease and to manage side effects caused by certain antipsychotic medications. It belongs to a class of drugs known as antimuscarinics, which help reduce muscle stiffness and improve movement.
Key Features
- Active Ingredient: Each tablet contains 5 mg of trihexyphenidyl hydrochloride.
- Formulation: Available in packs of 100 tablets, typically arranged in blister packs of 10 tablets each.
Indications
Benzhexol is indicated for:
- Parkinson’s Disease: Used as part of the treatment regimen to alleviate symptoms such as tremors, rigidity, and bradykinesia (slowness of movement).
- Drug-Induced Extrapyramidal Symptoms: Helps manage side effects similar to Parkinson’s disease that may arise from the use of certain medications, particularly antipsychotics.
Dosage and Administration
- Adults: The dosage should be tailored by a healthcare professional, typically starting at a low dose that is gradually increased. Commonly, the initial dose may start at 1 mg daily, with adjustments made based on response and tolerance.
- Maximum Dose: The maximum recommended daily dose is usually around 20 mg, divided into several doses throughout the day.
- Elderly Patients: Older adults may require lower doses due to increased sensitivity to medications.
Side Effects
Possible side effects may include:
- Drowsiness or dizziness
- Dry mouth
- Blurred vision
- Constipation
- Difficulty urinating
Warnings and Precautions
- Contraindications: Not suitable for individuals with known allergies to trihexyphenidyl or other antimuscarinic agents.
- Caution in Special Populations: Use with caution in patients with glaucoma, urinary retention, or gastrointestinal obstruction.
- Driving and Operating Machinery: May cause drowsiness; caution is advised when driving or operating heavy machinery.
Storage
Store Benzhexol tablets at room temperature (below 25°C), away from moisture and direct sunlight. Keep out of reach of children.
