Ampiclox is a combination antibiotic syrup that contains ampicillin and cloxacillin. This formulation is effective against a range of bacterial infections, particularly those caused by penicillin-sensitive organisms. It is commonly used in pediatric patients due to its liquid form, making it easier to administer.
Composition:
- Each 5 ml of syrup typically contains:
- 125 mg of Ampicillin
- 125 mg of Cloxacillin
Indications
Ampiclox is indicated for the treatment of:
- Respiratory Tract Infections: Such as pneumonia and bronchitis.
- Ear Infections: Including otitis media.
- Skin and Soft Tissue Infections: Effective against various skin infections.
- Urinary Tract Infections: Such as cystitis.
- Gastrointestinal Infections: Caused by susceptible strains.
Dosage
The recommended dosage for children is based on their age and weight:
- Children (2 to 12 years):
- Typically, the dosage is 5 to 10 ml every 6 hours, depending on the severity of the infection.
- Neonates to 2 years:
- The dosage may vary; consult a healthcare provider for specific recommendations.
Administration
- How to Take: Shake the bottle well before each use. Administer the syrup using a measuring spoon or syringe for accuracy.
- Missed Dose: If a dose is missed, give it as soon as you remember. If it's close to the next dose, skip the missed dose and continue with the regular schedule. Do not double up on doses.
Common Side Effects
Possible side effects may include:
- Nausea and vomiting
- Diarrhea
- Abdominal pain
- Rash or itching
Serious side effects are rare but can include:
- Severe allergic reactions (e.g., hives, difficulty breathing)
- Clostridium difficile-associated diarrhea
Warnings and Precautions
- Pregnant Women: Should consult a healthcare provider before use.
- Patients with Liver Disease or Renal Impairment: Caution is advised, and dosage adjustments may be necessary.
Drug Interactions
Ampiclox may interact with other medications, particularly:
- Anticoagulants: May enhance the effects of blood thinners like warfarin.
- Other Antibiotics: Use caution when combining with other antibiotics.
