Amlozaar H is a combination medication that includes amlodipine, losartan, and hydrochlorothiazide. This combination is primarily used for the management of hypertension (high blood pressure). Amlodipine is a calcium channel blocker that relaxes blood vessels, losartan is an angiotensin II receptor blocker that prevents blood vessel narrowing, and hydrochlorothiazide is a thiazide diuretic that helps reduce fluid retention.
Dosage Form:
- Strength: Each tablet contains 50 mg of losartan, 5 mg of amlodipine, and 12.5 mg of hydrochlorothiazide.
- Packaging: Typically available in packs of 30 tablets.
Indications
Amlozaar H is indicated for:
- Hypertension: Effective in lowering blood pressure to reduce the risk of cardiovascular events such as heart attack and stroke.
- Diabetic Nephropathy: Helps protect kidney function in patients with diabetes and high blood pressure.
- Heart Failure: May be used in patients with heart failure to help manage symptoms.
Dosage
The recommended dosage for adults is:
- Initial Dose: Usually, one tablet taken once daily. The dosage may be adjusted based on the patient's response and under the guidance of a healthcare provider.
Common Side Effects
Possible side effects may include:
- Dizziness or lightheadedness
- Fatigue
- Swelling of the legs or ankles (edema)
- Nausea or abdominal pain
- Increased urination
Serious side effects are rare but can include:
- Severe allergic reactions (e.g., rash, swelling)
- High potassium levels (hyperkalemia), which can cause muscle weakness or irregular heartbeat
- Symptoms indicating kidney problems (e.g., decreased urine output, swelling)
Warnings and Precautions
- Pregnant Women: Not recommended during pregnancy; consult a healthcare provider.
- Elderly Patients: May require monitoring for side effects due to increased sensitivity.
- Patients with Kidney or Liver Disease: Caution is advised, and dosage adjustments may be necessary.
Drug Interactions
Amlozaar H may interact with other medications, particularly:
- Potassium Supplements: Can increase potassium levels in the body.
- Other Antihypertensive Medications: May enhance blood pressure-lowering effects.
