Amlozaar is a combination medication that contains losartan and amlodipine, used primarily for the treatment of hypertension (high blood pressure). This combination works by relaxing blood vessels, which helps lower blood pressure and improve blood flow. It is particularly beneficial for patients with high blood pressure who may also have conditions such as diabetic nephropathy.
Dosage Form:
- Strength: 50 mg per tablet
- Packaging: Typically available in strips of 10 tablets, with a total of 30 tablets in this pack (3 x 10).
Indications
Amlozaar is indicated for:
- Hypertension: Effective in managing high blood pressure to reduce the risk of cardiovascular events.
- Diabetic Nephropathy: Helps slow kidney damage in patients with type 2 diabetes and high blood pressure.
- Stroke Prevention: Reduces the risk of stroke in patients with high blood pressure and left ventricular hypertrophy (thickening of the heart muscle).
Dosage
The recommended dosage for adults is:
- Initial Dose: Typically, one tablet (50 mg) taken once daily. The dose may be adjusted based on the patient's response and doctor's recommendations.
Common Side Effects
Possible side effects may include:
- Dizziness or lightheadedness
- Fatigue
- Swelling of the legs or ankles (edema)
- Nausea or abdominal pain
- Flushing
Serious side effects are rare but can include:
- Severe allergic reactions (e.g., swelling of the face, lips, or throat)
- High potassium levels (hyperkalemia), which can cause muscle weakness or irregular heartbeat
Warnings and Precautions
- Pregnant Women: Not recommended during pregnancy; consult a healthcare provider.
- Elderly Patients: May require monitoring for side effects due to increased sensitivity.
- Patients with Kidney or Liver Disease: Caution is advised, and dosage adjustments may be necessary.
Drug Interactions
Amlozaar may interact with other medications, particularly:
- Potassium Supplements: Can increase potassium levels in the body.
- Other Antihypertensive Medications: May enhance blood pressure-lowering effects.
