Atoxia contains etoricoxib, a selective COX-2 inhibitor classified as a non-steroidal anti-inflammatory drug (NSAID). It is primarily used to relieve pain and inflammation associated with various conditions, including arthritis and gout. Atoxia is effective in managing acute and chronic pain by inhibiting the enzyme responsible for producing prostaglandins, which are chemicals that promote inflammation and pain.
Indications
Atoxia 120 mg is indicated for:
- Acute Gouty Arthritis: Provides relief during acute gout attacks.
- Osteoarthritis: Manages pain and inflammation in osteoarthritis.
- Rheumatoid Arthritis: Helps alleviate symptoms associated with rheumatoid arthritis.
- Ankylosing Spondylitis: Used for managing pain and stiffness in ankylosing spondylitis.
- Chronic Musculoskeletal Pain: Effective in treating chronic pain conditions.
Dosage
- Acute Gout: The recommended dose is 120 mg once daily, limited to the acute painful period, typically not exceeding 8 days.
- Osteoarthritis and Rheumatoid Arthritis: The usual starting dose is 60 mg once daily, which may be increased to 90 mg once daily if necessary.
- Ankylosing Spondylitis: Initial dose of 60 mg once daily, with a possible increase to 90 mg once daily based on clinical response.
Administration
- How to Use: Atoxia tablets should be taken orally with a full glass of water. They can be taken with or without food. It is advisable to take the medication at the same time each day for consistent results.
- Missed Dose: If a dose is missed, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Common Side Effects
Possible side effects may include:
- Nausea
- Stomach pain or discomfort
- Diarrhea or constipation
- Headache
- Dizziness
- Swelling of the legs or ankles (peripheral edema)
Serious side effects, although rare, can include:
- Severe allergic reactions (e.g., rash, swelling, difficulty breathing)
- Increased blood pressure
- Gastrointestinal bleeding or ulcers
Warnings and Precautions
- Contraindications: Not suitable for individuals with known hypersensitivity to etoricoxib or those with active liver disease.
- Cardiovascular Risk: There may be an increased risk of heart attack and stroke associated with long-term use or high doses; monitoring by a healthcare provider is advised.
- Pregnancy and Breastfeeding: Consult a healthcare provider before use if you are pregnant or breastfeeding.
- Kidney Function: Caution is advised in patients with impaired kidney function.
Drug Interactions
Inform your healthcare provider about all medications you are taking, especially:
- Other NSAIDs or anticoagulants
- Medications that affect liver enzymes
Storage
Store Atoxia 120 mg tablets at room temperature (15° to 30°C), away from moisture and direct sunlight. Keep out of reach of children.
