Atorvastatin is a statin medication used primarily to lower cholesterol levels in the blood. It helps reduce the risk of cardiovascular diseases, including heart attacks and strokes, by inhibiting the enzyme HMG-CoA reductase, which plays a central role in cholesterol production in the liver.
Indications
Atorvastatin 10 mg is indicated for:
- Hyperlipidemia: Management of elevated total cholesterol, LDL cholesterol, apolipoprotein B, and triglycerides.
- Cardiovascular Risk Reduction: Used as an adjunct to diet to reduce the risk of heart attack and stroke in patients with risk factors.
Dosage
- Adults: The usual starting dose is 10 mg once daily, which may be adjusted based on response and lipid levels. The maximum dose is 80 mg per day.
- Children (10 years and older): The typical starting dose is also 10 mg once daily, with a maximum of 20 mg per day.
Administration
- How to Use: Atorvastatin tablets should be taken orally with a full glass of water. They can be taken at any time of day, with or without food, but should be taken consistently at the same time each day.
- Missed Dose: If a dose is missed, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up.
Common Side Effects
Possible side effects may include:
- Headache
- Nausea
- Diarrhea
- Constipation
- Muscle pain or weakness
- Fatigue
Serious side effects are less common but can include:
- Liver damage (indicated by symptoms such as dark urine or jaundice)
- Muscle damage (myopathy or rhabdomyolysis)
- Allergic reactions (e.g., rash, swelling)
Warnings and Precautions
- Contraindications: Not suitable for individuals with active liver disease or those allergic to atorvastatin.
- Pregnancy and Breastfeeding: Atorvastatin should not be used during pregnancy or while breastfeeding.
- Caution in Patients with Certain Conditions: Use with caution in patients with a history of liver disease, kidney problems, or those who consume large amounts of alcohol.
Drug Interactions
Inform your healthcare provider about all medications you are taking, especially:
- Other cholesterol-lowering medications
- Certain antibiotics and antifungals
- Medications for HIV or hepatitis C
Storage
Store Atorvastatin 10 mg tablets at room temperature (15° to 30°C), away from moisture and direct sunlight. Keep out of reach of children.
