All tetracyclines are about equally active and typically have about the same broad spectrum, which comprises both aerobic and anaerobic gram-positive and gram-negative bacteria, mycoplasmas, rickettsiae, chlamydiae, and even some protozoa (amebae). Strains of Pseudomonas aeruginosa,Proteus, Serratia, Klebsiella, and Arcanobacterium spp frequently are resistant, as are many pathogenic E coli isolates. diagnosis or treatment of bacterial infection that spreads from animals to people, eye infections and gut infection, infections with severe watery diarrhea .
