💧 Acetic Acid – Dilute Solvent for Peptide Reconstitution & pH Adjustment
Synonyms: Ethanoic Acid, Glacial Acetic Acid (diluted)
CAS Number: 64-19-7
Concentration: 0.6%–1.0% aqueous solution (typical for peptide use)
Form: Clear, sterile liquid
Research Use Only. Not for human consumption.
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Description:
Acetic Acid is a polar protic solvent widely used in peptide science to aid in the reconstitution of lyophilized peptides, particularly those with hydrophobic or acidic residues. When diluted to 0.6–1.0%, it serves as a pH-lowering agent that enhances solubility, disrupts peptide aggregation, and stabilizes delicate molecular conformations. It is especially useful for peptides like GHK-Cu, IGF variants, and long-chain metabolic analogs that resist dissolution in bacteriostatic water alone.
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⚙️ Functional Role in Research:
• Solubility Enhancer: Breaks hydrophobic interactions and peptide clumping
• pH Modulator: Lowers solution pH to improve dissolution of acidic or amphipathic peptides
• Stabilizer: Preserves peptide structure during reconstitution and short-term storage
• Carrier Compatibility: Often used in combination with bacteriostatic water for dual-phase solubilization
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📈 Research Applications:
Acetic Acid is routinely used in:
• Peptide reconstitution protocols for difficult-to-dissolve compounds
• Metal-binding peptide studies, such as GHK-Cu or MOTS-c
• pH-sensitive formulations requiring acidic environments
• Analytical chemistry workflows, including HPLC and CE sample prep
Its role is especially critical in preserving peptide integrity during the initial solubilization phase.
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📦 Packaging & Handling:
Supplied in sterile, sealed vials (typically 3ml or 10ml). Store at room temperature, away from light and moisture. Use aseptic technique when withdrawing. Discard within 28 days of opening if sterility is compromised.
SKU: AAC-006PCT-VIAL
