🧬 Retagri – Quad-Pathway Metabolic Modulator (GLP-1 + GIP + Glucagon + Amylin)
Synonyms: Retatrutide + Cagrilintide Hybrid
Form: Lyophilized peptide blend
Purity: ≥98% (HPLC)
Research Use Only. Not for human consumption.
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Description:
Retagri is a conceptual multi-receptor peptide formulation that blends the triple agonist properties of Retatrutide—targeting GLP-1R, GIPR, and GCGR—with the satiety-enhancing amylin/calcitonin receptor agonism of Cagrilintide. This strategic pairing is designed to engage four metabolic hormone pathways, supporting investigations into appetite regulation, glycemic control, and energy expenditure.
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⚙️ Mechanism of Action:
Retagri activates GLP-1 receptors to stimulate insulin secretion, delay gastric emptying, and suppress glucagon. Its GIP receptor engagement supports postprandial insulin sensitivity. The glucagon receptor pathway boosts thermogenesis and fat oxidation, while amylin receptor activation promotes satiety and regulates gastric motility. Together, these mechanisms create a synchronized hormonal response that mimics and amplifies the body’s natural reaction to food intake.
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📈 Research Applications:
Retagri is under conceptual investigation for use in models exploring multi-hormonal interventions. These include studies on obesity, where both appetite suppression and metabolic acceleration are required; insulin resistance and visceral adiposity; and long-term remodeling of energy homeostasis. It may also offer insight into optimal dosing strategies for combination peptide regimens.
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📦 Packaging & Handling:
Supplied as a sterile-filtered lyophilized peptide blend. Store at –20°C, away from light and moisture. Reconstitute using bacteriostatic water or acetic acid. After reconstitution store in a refrigerator to preserve stability and biological activity 2-8°C
SKU: RTG-5MG500MCG-PEN-DSP
