🧬 BPC-157 – Regenerative Peptide for Angiogenesis, Tissue Repair & Gastrointestinal Research
Synonyms: Body Protection Compound-157, PL 14736
CAS Number: 137525-51-0
Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Molecular Weight: ~1419.5 Da
Form: Lyophilized powder
Purity: ≥98% (HPLC)
Research Use Only. Not for human consumption.
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Description:
BPC-157 is a synthetic pentadecapeptide derived from a partial sequence of Body Protection Compound (BPC), a protein naturally found in human gastric juice. It is under active investigation for its multifaceted regenerative properties, particularly in models of muscle, tendon, nerve, and gastrointestinal repair. BPC-157 is known to modulate angiogenesis, collagen synthesis, and inflammatory signaling, making it a versatile scaffold in wound healing and organoprotection research.
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⚙️ Mechanism of Action:
Although not fully elucidated, BPC-157 is believed to act through several converging pathways:
• VEGF Upregulation: Promotes angiogenesis and microvascular repair
• Fibroblast Activation: Enhances collagen production and extracellular matrix remodeling
• Anti-Inflammatory Modulation: Downregulates pro-inflammatory cytokines (e.g., TNF-α, IL-6)
• Neuroregeneration: Supports axonal outgrowth and synaptic repair in peripheral nerve models
• Gastrointestinal Protection: Accelerates healing of ulcers and mitigates NSAID-induced mucosal damage
Its systemic effects have been observed in both local injury models and systemic inflammatory conditions.
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📈 Research Applications:
BPC-157 is being explored in preclinical and in vitro models for:
• Tendon-to-bone healing and ligament repair
• Skeletal muscle regeneration and myocyte protection
• Gastrointestinal mucosal healing (e.g., IBD, ulcers)
• Peripheral nerve injury and neuroinflammation
• Joint health and arthritis models
• Angiogenesis and ischemic tissue recovery
Its non-anabolic, non-hormonal profile makes it suitable for diverse regenerative studies without endocrine disruption.
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📦 Packaging & Handling:
• Supplied as a sterile-filtered lyophilized peptide
• Store at –20°C, protected from light and moisture
• Reconstitute with bacteriostatic water, acetic acid, or appropriate diluent
• Store in the refrigerator once in a reconstituted solution to preserve bioactivity 2-8°C
SKU: BPC-20MG-VIAL
