The pomelo is one of the original citrus species from which cultivated citrus fruits have been hybridized, others being citron, mandarin, and to a lesser extent, papedas and kumquat. In particular, the common orange is presumed to be a naturally occurring hybrid between the pomelo and the mandarin with the pomelo providing the larger size and greater firmness. The grapefruit was originally also presumed to be a naturally occurring hybrid of the pomelo and the mandarin; however, genome analysis conducted more than two centuries after this presumption was made shows that it is actually a backcrossed hybrid between a pomelo and a sweet orange which is why 63% of the grapefruit's genome comes from the pomelo.
柚子是杂交栽培柑橘类水果的原始柑橘品种之一，其他品种是柚子、柑橘，以及在较小程度上，papedas 和金橘。 特别是，普通橙被认为是柚子和普通话之间的天然杂交种，柚子提供更大的尺寸和更大的硬度。 葡萄柚最初也被认为是柚子和柑橘的天然杂交种。 然而，在做出这一假设两个多世纪后进行的基因组分析表明，它实际上是柚子和甜橙之间的回交杂交种，这就是为什么 63% 的柚子基因组来自柚子的原因。
