Mounjaro 10 mg KwikPen:
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🖊️ What It Is
• Active Ingredient: Tirzepatide – a dual-action GIP + GLP‑1 receptor agonist. This means it mimics two natural gut hormones to promote insulin release, reduce blood sugar, and suppress appetite .
• Brand: Mounjaro (by Eli Lilly), approved as an injectable for type 2 diabetes, and authorized for weight management in the UK and US .
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💉 Pen Details
• Strength: Each dose delivers 10 mg of tirzepatide in a 0.6 mL injection.
• Pen Content: The refillable pen holds 40 mg total in 2.4 mL, providing 4 doses per pen .
• Form: Clear to slightly yellow solution in a multi-dose KwikPen—no needle handling or mixing required .
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🕐 Dosage & Administration
• Frequency: Once-weekly subcutaneous injection (abdomen, thigh, upper arm) .
• Start: Typically begins at 2.5 mg/week and increases every 4 weeks, eventually reaching the 10 mg maintenance dose .
• Missed Dose: Can be taken within 4 days of missed dose; after that, resume regular schedule—no double dosing .
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🧪 Mechanism of Action
• Dual Incretin Effect: Stimulates insulin secretion and improves insulin sensitivity by activating both GIP and GLP‑1 receptors—resulting in stronger blood sugar control and often greater weight loss than GLP‑1–only medications .
• Weight Loss Evidence: Clinical trials show significant reductions in HbA1c and body weight—SURPASS‑2 reported A1C drops of 2.0–2.3% and weight loss of 7.7–11.4 kg (17–25 lb) with the 10 mg dose .
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⚠️ Safety & Side Effects
• Common Side Effects:
• Gastrointestinal – nausea, vomiting, diarrhea, constipation, indigestion 
• Warnings:
• Not for type 1 diabetes or those with a history of pancreatitis.
• Contraindicated in people with medullary thyroid carcinoma or multiple endocrine neoplasia type 2  .
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🔄 Storage & Handling
• Before Use: Store in fridge (2–8 °C); protect from light. Do not freeze .
• Portability: After removal from refrigeration, pen stable at up to 30 °C for 21 days .
• Discard: Replace pen after 4 full doses; follow local disposal guidelines .
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🎯 Summary
• Indication: Weekly injectable for type 2 diabetes, with off-label use for weight loss.
• Format: Multi-dose pen delivering 10 mg per injection (0.6 mL), with 4 doses per pen.
• Mechanism: Dual GIP+GLP‑1 action enhances glycemic control and appetite suppression.
• Benefits: Significant HbA1c lowering and body weight reduction.
• Side Effects: Mainly GI issues; has thyroid, pancreatitis, and hypoglycemia warnings.
