Retatrutide 12 mg is a high dose of this triple hormone receptor agonist, which has shown significant promise in weight loss and metabolic health management. Here's what we know about this dosage:
Weight Loss Results:
- In a 48-week phase 2 trial, participants receiving 12 mg of retatrutide per week experienced an average weight loss of 24.2% of their starting weight.
- A significant portion of participants (64-100%) achieved meaningful weight loss of 5% or more ¹.
Administration and Dosage Schedule:
- The typical dosage schedule starts with a low dose (0.5-2.5 mg) and gradually increases every 4 weeks to minimize side effects.
- The dose escalation schedule may look like this:
- Weeks 1-4: 0.5-2.5 mg
- Weeks 5-8: 2-5 mg
- Weeks 9-12: 4-10 mg
- Weeks 13+: 8-12 mg
