Administration: The pen is designed for ease of use, often featuring a side-activation mechanism and dose selector with audible clicks and visual markers for accurate dosing. Injections are rotated across sites (e.g., stomach, thigh, upper arm) to prevent irritation.The pen is pre-filled with retatrutide, sometimes reconstituted with bacteriostatic water for stability.
Dosage: Dosing starts low (e.g., 1–2.5 mg weekly) to minimize side effects, with gradual increases (titration) every few weeks, potentially up to 8–12 mg, depending on patient response and trial protocols.
Storage: Unopened pens must be refrigerated (36°F–46°F or 2°C–8°C) in their original carton to protect from light. For travel, pens can be kept at room temperature (up to 86°F or 30°C) for up to 21 days but should not be returned to the fridge afterward. Freezing must be avoided, as it compromises efficacy.
