Liothyronine is a form of thyroid hormone used to treat hypothyroidism and myxedema coma. Liothyronine is the most potent form of thyroid hormone. Chemically, it is nearly identical to triiodothyronine(T3). As such, it acts on the body to increase the basal metabolic rate, effect protein synthesis and increase the body's sensitivity to catecholamines (such as adrenaline) by permissiveness. The thyroid hormones are essential to proper development and differentiation of all cells of the human body. These hormones also regulate protein, fat, and carbohydrate metabolism, affecting how human cells use energetic compounds.