MOTS-C is a 16-amino-acid peptide encoded within mitochondrial DNA that helps regulate cellular metabolism and energy balance.
Mitochondrial Origin: MOTS-c stands for mitochondrial open reading frame of the 12S rRNA type-c. Unlike most peptides, your mitochondria—the energy generators of cells—produce it naturally.
Metabolic Regulator: It acts as a signaling molecule or "mitokine" that helps tissues manage fuel, respond to stress, and adjust glucose and fat handling.
Exercise Connection: Levels of MOTS-c change in response to physical activity and metabolic stress, leading researchers to study it as an exercise mimetic (a compound that triggers some similar metabolic pathways)
For research and educational purposes only.