Mechanism: Activates GLP-1 and GIP receptors to enhance insulin secretion, reduce liver glucose production, and slow gastric emptying, lowering blood sugar and HbA1c.
Dosing: Administer once weekly, any time of day, with or without food. If a dose is missed, take within 4 days; otherwise, skip and resume the schedule. Rotate injection sites to prevent irritation.
Efficacy: Clinical trials show 75–90% of patients achieve HbA1c <7% on 5 mg, with fasting glucose reductions of ~40–58 mg/dL. Weight loss (12–25 lbs across doses) is common but not FDA-approved for this; Zepbound is approved for weight loss.
