Salmeterol and Fluticasone Propionate Powder for Inhalation IP
Composition:
Each inhalation device (blister or canister) contains a combination of:
Salmeterol Xinafoate 50mcg
Fluticasone Propionate 100mcg, 250mcg, or 500mcg (depending on the formulation)
Indications:
Salmeterol and Fluticasone Propionate Powder for Inhalation is indicated for the long-term treatment of asthma and chronic obstructive pulmonary disease (COPD). This combination is used to improve symptoms of asthma, including wheezing and shortness of breath, and to reduce the frequency of asthma attacks. It is also used to treat COPD, helping to prevent bronchospasm and reduce inflammation in the airways, making breathing easier for patients with chronic lung diseases.
Mechanism of Action:
Salmeterol is a long-acting beta-agonist (LABA) that works by relaxing the muscles in the airways and dilating the bronchi, helping to keep the airways open. This action provides bronchodilation for up to 12 hours, helping to alleviate symptoms of wheezing, tightness, and breathlessness.
Fluticasone Propionate is a corticosteroid that reduces inflammation in the airways, decreasing swelling, mucus production, and bronchoconstriction. This helps to prevent asthma attacks and exacerbations in COPD by reducing the underlying inflammation and hyperresponsiveness of the airways.
The combination of Salmeterol and Fluticasone provides both bronchodilation and anti-inflammatory effects, making it effective for controlling both the symptoms and underlying inflammation of asthma and COPD.
Dosage:
The recommended dose for Salmeterol and Fluticasone Propionate Powder for Inhalation depends on the individual’s condition and response to therapy:
Asthma: Typically, one inhalation of 50mcg/100mcg or 50mcg/250mcg twice daily.
COPD: One inhalation of 50mcg/250mcg or 50mcg/500mcg twice daily.
The dosage should be adjusted based on clinical response and the severity of symptoms. Patients should not exceed one inhalation twice daily (morning and evening).
Packaging:
Salmeterol and Fluticasone Propionate Powder for Inhalation is available in blister packs or inhaler devices, with the specific dosage strength depending on the prescribed formulation (e.g., 100mcg, 250mcg, or 500mcg fluticasone with 50mcg salmeterol per dose). Each pack typically contains 30 or 60 doses, depending on the formulation.
